Endocrine Abstracts

Background: Recent therapeutic advances have resulted in prolonged survival of thalassemia major patients reaching adulthood and attaining reproductive capacity. However, endocrine complications are commoner in thalassemia major patients with up to 30% of patients showing hypogonadotrophic hypogonadism. Although spontaneous pregnancy have been described in well chelated and transfused patients, majority of thalassemia major patients are infertile and need assisted reproductive...